Caspase-10 Polyclonal Antibody
簡(jiǎn)要描述:Caspase-10 Polyclonal Antibody宿主: Polyclonal, Rabbit,IgG反應性: Human;Rat;Mouse;應用: WB;ELISA
產(chǎn)品型號: YP-Ab-00561
所屬分類(lèi):多克隆抗體
更新時(shí)間:2023-10-19
詳細說(shuō)明:
Caspase-10 Polyclonal Antibody
抗體,也叫免疫球蛋白(Ig),是一種能特異性結合抗原的糖蛋白,而抗原是在易感染動(dòng)物體內引發(fā)抗體產(chǎn)生的物質(zhì)。在體內,抗體是由于外源性分子的侵襲而產(chǎn)生的??贵w以一個(gè)或者多個(gè)Y字形單體存在,每個(gè)Y字形單體由4條多肽鏈組成,包含兩條相同的重鏈和兩條相同的輕鏈。輕鏈和重鏈是根據它們的分子量大小來(lái)命名的。Y字形結構的頂端是可變區,為抗原結合部位。任何一個(gè)抗體的輕鏈都可以分為κ或λ型(基于小分子多肽結構上的差異),每一個(gè)抗體的重鏈則決定了它的類(lèi)或型。
產(chǎn)品詳情
Caspase-10 Polyclonal Antibody detects endogenous levels of Caspase-10 protein.
免疫原詳細信息
Synthesized peptide derived from the Internal region of human Caspase-10.
相關(guān)試劑
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
背景
This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 3 and 7, and the protein itself is processed by caspase 8. Mutations in this gene are associated with type IIA autoimmune lymphoproliferative syndrome, non-Hodgkin lymphoma and gastric cancer. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Apr 2011]
天津俊達生物科技有限公司,是從事實(shí)驗室耗材銷(xiāo)售的現代化生物科技企業(yè),公司本著(zhù)“誠信為本,互利共贏(yíng)"的核心價(jià)值觀(guān),秉承“以市場(chǎng)為導向,提供服務(wù)"的宗旨為各大院校、科研單位、第三方實(shí)驗室檢測機構等提供的產(chǎn)品和服務(wù)。目前公司主要經(jīng)營(yíng)分子生物學(xué)、細胞生物學(xué)、免疫學(xué)等生物學(xué)產(chǎn)品,多種實(shí)驗室耗材 歡迎垂詢(xún)!
備注:圖片僅供參考。僅供科研,不可用于臨床。