Ku-80 Monoclonal Antibody
簡(jiǎn)要描述:Ku-80 Monoclonal Antibody宿主: Monoclonal, Mouse反應性: Human;Mouse應用: WB;IHC;IF;FCM;ELISA
產(chǎn)品型號: YP-Ab-00069
所屬分類(lèi):單克隆抗體
更新時(shí)間:2023-10-26
詳細說(shuō)明:
Ku-80 Monoclonal Antibody
抗體,也叫免疫球蛋白(Ig),是一種能特異性結合抗原的糖蛋白,而抗原是在易感染動(dòng)物體內引發(fā)抗體產(chǎn)生的物質(zhì)。在體內,抗體是由于外源性分子的侵襲而產(chǎn)生的??贵w以一個(gè)或者多個(gè)Y字形單體存在,每個(gè)Y字形單體由4條多肽鏈組成,包含兩條相同的重鏈和兩條相同的輕鏈。輕鏈和重鏈是根據它們的分子量大小來(lái)命名的。Y字形結構的頂端是可變區,為抗原結合部位。任何一個(gè)抗體的輕鏈都可以分為κ或λ型(基于小分子多肽結構上的差異),每一個(gè)抗體的重鏈則決定了它的類(lèi)或型。
產(chǎn)品詳情
Ku-80 Monoclonal Antibody detects endogenous levels of Ku-80 protein.
免疫原詳細信息
Purified recombinant fragment of human Ku-80 expressed in E. Coli.
相關(guān)試劑
Ascitic fluid containing 0.03% sodium azide,0.5% BSA, 50%glycerol.
背景
The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V(D)J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. [provided by RefSeq, Jul 2008]
天津俊達生物科技有限公司,是從事實(shí)驗室耗材銷(xiāo)售的現代化生物科技企業(yè),公司本著(zhù)“誠信為本,互利共贏(yíng)"的核心價(jià)值觀(guān),秉承“以市場(chǎng)為導向,提供服務(wù)"的宗旨為各大院校、科研單位、第三方實(shí)驗室檢測機構等提供的產(chǎn)品和服務(wù)。目前公司主要經(jīng)營(yíng)分子生物學(xué)、細胞生物學(xué)、免疫學(xué)等生物學(xué)產(chǎn)品,多種實(shí)驗室耗材 歡迎垂詢(xún)!
備注:圖片僅供參考。僅供科研,不可用于臨床。